师资介绍 梁世德 副教授

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梁世德　副教授

姓名梁世德

出生年月 1971年10月24日

职称副教授

简历（从大学开始）

1989.9-1993.7 浙江大学生物科学与技术系本科生, 获学士学位 1993.9-1996.7 中科院海洋所海洋生物专业,获硕士学位 1996.9-2000.7 北京大学物理化学专业,获博士学位 1 o' m6 S. i% |5 k

2000.8-2002.8 美国德州大学西南医学研究中心博士后

2002.9至今 中国海洋大学副教授

研究方向生物信息学

最近课题蛋白质界面残基的能量分析

主要论文 0 H' N# g; Z# L4 t: y) d9 @1. Shide Liang, Jian Zhang, Shicui Zhang, and Huarong Guo Prediction of the interaction site on the surface of an isolated protein structure by analysis of side chain energy scores. 2004 Proteins 57：548-57 5 {' K' h. Z* H* |3 ^2. Shide Liang and Nick V. Grishin Effectvie scoring funcion for protein sequence design. 2004 Proteins 54:271-281 5 g# S1 L' W1 q2 x* S( `: c$ ?3. Liu Zhijie, Jiang Lin, Gao Ying, Liang Shide, Chen Hao, Han Yuzhen and Lai Luhua, Beyond the rotamer library: genetic algorithm combined with the disturbing mutation process for upbuilding protein side-chains.2003 Proteins 50:49-62 " U6 F1 x4 `# ~4. Shide Liang and Nick V. Grishin Side-chain modeling with an optimized scoring function. Protein Sci 2002 11: 322-33 5. Shide Liang, Zhijie Liu, and Luhua Lai, Construction of protein binding sites in scaffold structures. Biopolymers 2000 54:515-523 6. Shide liang, Weizhong Li, Lan Xiao, Jiansuo Wang, and Luhua Lai, Grafting of Protein-Protein interaction epiope. Journal ofBiomolecular Structure & Dynamics 2000 17:821-838 7. LIANG Shide,XIAO Lan,MAO Fenglou,JIANG Lin, Han Yuzhen, and LAI Luhua, Grafting of protein binding site. Chinese Science Bulletin 2000 45:1707-1711 8. Weizhong Li, Shide Liang, Renxiao Wang, Luhua Lai, and Yuzhen Han, Exploring the conformational diversity of loops on conserved frameworks. Protein Eng 1999 12: 1075-1086 9.LI Weizhong,LIU Zhijie,LIANG Shide,HAN Yuzhen and LAI Luhua,Rational screen in combinatorial peptide libraries of protein functional loop. Chinese science Bulletin 1999 44:2150-2154

联系电话 13306482002

Email shideliang@hotmail.com

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